Rena Fragiadaki
Experienced Technicians,
Haemopoiesis Research Laboratory
School of Medicine, University of Crete
Tel: (+30) 2810-394629
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
EDUCATION
BSc, Biochemistry (2000), School of Environment and Life Sciences, University of Salford, Manchester, UK
PhD candidate, Laboratory of Clinical Bacteriology, Parasitology, Zoonoses & Geographical Medicine, School of Medicine, University of Crete, Greece
RESEARCH INTEREST
Investigation of DUFFY/DARC polymorphism in patients with neutropenia
POSITION
Experienced Technician/ Lab assistant in the Haemopoiesis Research Laboratory, School of Medicine, University of Crete, Greece
Staff member of the Public Cord Blood Bank
SELECTED PUBLICATIONS
The resveratrol analogue, 3,4,5,4'‑trans-tetramethoxystilbene, inhibits the growth of A375 melanoma cells through multiple anticancer modes of action. Androutsopoulos VP, Fragiadaki I, Spandidos DA, Tosca A. Int J Oncol. 2016: 1305-14
Synthesis and biological evaluation of trifluralin analogues as antileishmanial agents. Esteves MA, Fragiadaki I, Lopes R, Scoulica E, Cruz ME. Bioorg Med Chem. 2010: 274-81
KIT receptor activation by autocrine and paracrine stem cell factor stimulates growth of merkel cell carcinoma in vitro. Krasagakis K, Fragiadaki I, Metaxari M, Krüger-Krasagakis S, Tzanakakis GN, Stathopoulos EN, Eberle J, Tavernarakis N, Tosca AD. J Cell Physiol. 2011: 1099-109
Activation of ERK1/2 is required for the antimitotic activity of the resveratrol analogue 3,4,5,4'-tetramethoxystilbene (DMU-212) in human melanoma cells. Androutsopoulos VP, Fragiadaki I, Tosca A. Exp Dermatol. 2015: 632-4
Design and synthesis of potent antileishmanial cycloalkylidene-substituted ether phospholipid derivatives. Calogeropoulou T, Angelou P, Detsi A, Fragiadaki I, Scoulica E. J Med Chem. 2008: 897-908
The role of endothelial cell apoptosis in the effect of etanercept in psoriasis. Avramidis G, Krüger-Krasagakis S, Krasagakis K, Fragiadaki I, Kokolakis G, Tosca A. Br J Dermatol. 2010: 928-34
Structure-activity relationships of antineoplastic ring-substituted ether phospholipid derivatives. Papazafiri P, Avlonitis N, Angelou P, Calogeropoulou T, Koufaki M, Scoulica E, Fragiadaki I. Cancer Chemother Pharmacol. 2005: 261-70
EDUCATION
· BSc, Biochemistry (2000), School of Environment and Life Sciences, University of Salford, Manchester, UK
· PhD candidate, Laboratory of Clinical Bacteriology, Parasitology, Zoonoses & Geographical Medicine, School of Medicine, University of Crete, Greece
RESEARCH INTEREST
· Investigation of DUFFY/DARC polymorphism in patients with neutropenia
POSITION
· Experienced Technician/ Lab assistant in the Haemopoiesis Research Laboratory, School of Medicine, University of Crete, Greece
· Staff member of the Public Cord Blood Bank
SELECTED PUBLICATIONS
The resveratrol analogue, 3,4,5,4'‑trans-tetramethoxystilbene, inhibits the growth of A375 melanoma cells through multiple anticancer modes of action. Androutsopoulos VP, Fragiadaki I, Spandidos DA, Tosca A. Int J Oncol. 2016: 1305-14
Synthesis and biological evaluation of trifluralin analogues as antileishmanial agents. Esteves MA, Fragiadaki I, Lopes R, Scoulica E, Cruz ME. Bioorg Med Chem. 2010: 274-81
KIT receptor activation by autocrine and paracrine stem cell factor stimulates growth of merkel cell carcinoma in vitro. Krasagakis K, Fragiadaki I, Metaxari M, Krüger-Krasagakis S, Tzanakakis GN, Stathopoulos EN, Eberle J, Tavernarakis N, Tosca AD. J Cell Physiol. 2011: 1099-109
Activation of ERK1/2 is required for the antimitotic activity of the resveratrol analogue 3,4,5,4'-tetramethoxystilbene (DMU-212) in human melanoma cells. Androutsopoulos VP, Fragiadaki I, Tosca A. Exp Dermatol. 2015: 632-4
Design and synthesis of potent antileishmanial cycloalkylidene-substituted ether phospholipid derivatives. Calogeropoulou T, Angelou P, Detsi A, Fragiadaki I, Scoulica E. J Med Chem. 2008: 897-908
The role of endothelial cell apoptosis in the effect of etanercept in psoriasis. Avramidis G, Krüger-Krasagakis S, Krasagakis K, Fragiadaki I, Kokolakis G, Tosca A. Br J Dermatol. 2010: 928-34
Structure-activity relationships of antineoplastic ring-substituted ether phospholipid derivatives. Papazafiri P, Avlonitis N, Angelou P, Calogeropoulou T, Koufaki M, Scoulica E, Fragiadaki I. Cancer Chemother Pharmacol. 2005: 261-70