Curriculum vitae
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Helen Koutala Education: Agricultural Technologist of TEI Heraklion. Recruitment in medical school at the University of Crete (06.05.1992). I work as a laboratory technician at the flow cyttometry laboratory. |
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Research activity:
1.Increased Levels of the High Mobility Group Box 1 Protein Sustain the Inflammatory Bone Marrow Microenvironment in Patients with Chronic Idiopathic Neutropenia via Activation of Toll-Like Receptor 4.
Velegraki M, Koutala H, Tsatsanis C, Papadaki HA.J Clin Immunol. 2011 Nov 30. [Epub ahead of print]
2.Lymphopenia in patients with chronic idiopathic neutropenia is associated with decreased number of T-lymphocytes containing T-cell receptor excision circles.
Gemetzi C, Mavroudi I, Koutala H, Velegraki M, Choulaki C, Damianaki A, Pontikoglou C, Papadaki HA.
Eur J Haematol. 2011 Oct 14. doi: 10.1111/j.1600-0609.2011.01722.x. [Epub ahead of print]
3.Investigation of Toll-like receptors in the pathogenesis of fibrotic and granulomatous disorders: a bronchoalveolar lavage study.
Margaritopoulos GA, Antoniou KM, Karagiannis K, Samara KD, Lasithiotaki I, Vassalou E, Lymbouridou R, Koutala H, Siafakas NM.
Fibrogenesis Tissue Repair. 2010 Oct 11;3:20.
4.T-cell receptor Vβ repertoire analysis in patients with chronic idiopathic neutropenia demonstrates the presence of aberrant T-cell expansions.
Spanoudakis M, Koutala H, Ximeri M, Pyrovolaki K, Stamatopoulos K, Papadaki HA.
Clin Immunol. 2010 Dec;137(3):384-95. Epub 2010 Sep 22.
5.Investigation of bone marrow mesenchymal stem cells (BM MSCs) involvement in Idiopathic Pulmonary Fibrosis (IPF).
Antoniou KM, Papadaki HA, Soufla G, Kastrinaki MC, Damianaki A, Koutala H, Spandidos DA, Siafakas NM.
Respir Med. 2010 Oct;104(10):1535-42. Epub 2010 May 18.
6.Leishmania donovani s.l.: evaluation of the proliferation potential of promastigotes using CFSE staining and flow cytometry.
Messaritakis I, Mazeris A, Koutala E, Antoniou M.
Exp Parasitol. 2010 Aug;125(4):384-8. Epub 2010 Mar 19.
7.Maintained smoking cessation for 6 months equilibrates the percentage of sputum CD8+ lymphocyte cells with that of nonsmokers.
Bouloukaki I, Tsoumakidou M, Vardavas CI, Mitrouska I, Koutala E, Siafakas NM, Schiza SE, Tzanakis N.
Mediators Inflamm. 2009;2009:812102. Epub 2010 Feb 23.
8.Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response.
NakouM, KatsikasG, SidiropoulosP, BertsiasG, PapadimitrakiE, RaptopoulouA, KoutalaH, PapadakiHA, KritikosH, BoumpasDT.
Arthritis Res Ther. 2009;11(4):R131. Epub 2009 Aug 28.
9.Decreased sputum mature dendritic cells in healthy smokers and patients with chronic obstructive pulmonary disease.
Tsoumakidou M, Bouloukaki I, Koutala H, Kouvidi K, Mitrouska I, Zakynthinos S, Tzanakis N, Jeffery PK, Siafakas NM.
Int Arch Allergy Immunol. 2009;150(4):389-97. Epub 2009 Jul 1.
10.Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune process.
Papadimitraki ED, Choulaki C, Koutala E, Bertsias G, Tsatsanis C, Gergianaki I, Raptopoulou A, Kritikos HD, Mamalaki C, Sidiropoulos P, Boumpas DT.Arthritis Rheum. 2006 Nov;54(11):3601-11.
11.Isolation of myeloid and plasmacytoid dendritic cells from human bronchoalveolar lavage fluid.
Tsoumakidou M, Tzanakis N, Papadaki HA, Koutala H, Siafakas NM.
Immunol Cell Biol. 2006 Jun;84(3):267-73.
12.An open label, single dose study to evaluate the safety, efficacy, and effects on CD25 expression of ciclosporin in patients with active rheumatoid arthritis despite treatment with methotrexate and infliximab.
Sidiropoulos PI, Siakka P, Raptopoulou A, Mamoulaki M, Choulaki C, Koutala H, Kouroumali H, Kritikos H, Boumpas DT.
Ann Rheum Dis. 2006 Apr;65(4):538-41. Epub 2005 Aug 26.
13.Micromolar taxol, with or without hyperthermia, induces mitotic catastrophe and cell necrosis in HeLa cells.
Michalakis J, Georgatos SD, Romanos J, Koutala H, Georgoulias V, Tsiftsis D, Theodoropoulos PA.
Cancer Chemother Pharmacol. 2005 Dec;56(6):615-22. Epub 2005 Jul 16.
14.Impaired granulocytopoiesis in patients with chronic idiopathic neutropenia is associated with increased apoptosis of bone marrow myeloid progenitor cells.
Papadaki HA, Eliopoulos AG, Kosteas T, Gemetzi C, Damianaki A, Koutala H, Bux J, Eliopoulos GD.
Blood. 2003 Apr 1;101(7):2591-600. Epub 2002 Nov 27.
15.Bone marrow progenitor cell reserve and function and stromal cell function are defective in rheumatoid arthritis: evidence for a tumor necrosis factor alpha-mediated effect.
Papadaki HA, Kritikos HD, Gemetzi C, Koutala H, Marsh JC, Boumpas DT, Eliopoulos GD.Blood. 2002 Mar 1;99(5):1610-9. Erratum in: Blood. 2007 May 15;109(10):4180.
16.Drug Resistance in Natural Isolates of Leishmania donovani s.l. Promastigotes Is Dependent of Pgp170 Expression
Ippokratis Messaritakis, Vasiliki Christodoulou, Apostolos Mazeris, Eleni Koutala, Antonia Vlahou, Sevasti Papadogiorgaki, Maria Antoniou
PLoS One. 2013; 8(6): e65467. Published online 2013 June 11. doi: 10.1371/journal.pone.0065467 PMCID: PMC3679129
Special Issue on MDSCs
