CURRENT POSITION:

	Haemopoiesis Research Laboratory   School of Medicine, University of Crete Phone: + 30 2810 39278 E-mail: eri.boutakoglou_AT_gmail.com

Education

• 2008-2011: High School Certificate
• 2011-2017: Faculty of Medicine, School of Life Sciences, University of Ioannina, Greece (Excellent – 8.63 / 10.0)
• 2018-2020: Resident of Internal Medicine, University Hospital of Crete, Greece
• 2020-today: Resident of Hematology, University Hospital of Crete, Greece

Languages

• 2007: Edexcel Level I Certificate ESOL International (B2)
• 2007: Zertifikat Deutsch (B1)

Educational Interests

Clinical, laboratory and prognostic characteristics of subgroups of patients with chronic idiopathic neutropenia based on the neutrophil immunological profile and mutational status of genes associated with benign or clonal haemopoiesis- Haemopoiesis Research Laboratory, Medical School, University of Crete, Greece

Publications

• Zervakis SG, Spernovasilis N, Boutakoglou E, Panagiotakis S, Thomopoulou K, Samonis G. Erythroderma as a paraneoplastic manifestation of small cell lung cancer. Curr Probl Cancer. 2020 Apr; 44(2):100499. doi: 10.1016/j.currproblcancer.2019.100499. Epub 2019 Aug 30. PMID: 31493907.

	Haemopoiesis Research Laboratory Schoolof Medicine, University of Crete Phone: + 30 2810 394637 FAX: + 30 2810 394632                                                                                  Email: damianak [at] uoc.gr

EDUCATION:

• Degree as “Medical and Biology Laboratory Assistant” (1994) Technical School, Heraklion, Crete
• Certificate in “Basic Training in Flow Cytometry and applications in Hematology”, (2013), Hellenic Cytometry Society

POSITION:

• Technician/ Lab assistant in the Haemopoiesis Research Laboratory, School of Medicine, University of Crete, Greece
• Assistant in the Autologous Transplantation Unit, Haematology Department of the University Hospital of Heraklion
• Participation in Cord Blood Bank

PROFESSIONAL EXPERIENCE:

• 4 years experience in the Experimental Endocrinology laboratory (Faculty of Medicine, University of Grete).
• Since May 2000, technician in the Haematology laboratory of the Faculty of Medicine in the University of Crete.

RESEARCH INTERESTS :

• Haemopoietic Stem Cells and effect of the BM microenvironment in BM failure syndromes
• Humoral immunity in Chronic Idiopathic Neutropenia
• Identification of PNH type cells in patients with Chronic Idiopathic Neutropenia

SELECTED PUBLICATIONS:

1. Damianaki A,Stagakis E,Mavroudi I, Spanoudakis M, Koutala H, Papadogiannis F,kanellou P,Pontikoglou C, Papadaki HA. Minor populations of paroxysmal nocturnal haemoglobinuria type cells in patients with chronic idiopathic neutropenia.  Eur J Haematol. 2016 Apr 28. doi: 10.1111/ejh.12766 PMID: 27124520
2. Pavlaki K, Pontikoglou CG, Demetriadou A, Batsali AK, Damianaki A, Simantirakis E, Kontakis M, Galanopoulos A, Kotsianidis I, Kastrinaki MC, Papadaki HA .Impaired proliferative potential of bone marrow mesenchymal stromal cells in patients with myelodysplastic syndromes is associated with abnormal WNT signaling pathway Stem Cells Dev. 2014 Jul 15;23(14):1568-81. doi: 10.1089/scd.2013.0283. Epub 2014 Apr 2 PMID:24617415
3. Gemetzi C, Mavroudi I, Koutala H, Velegraki M, Choulaki C, Damianaki A, Pontikoglou C, Papadaki HA. Lymphopenia in patients with chronic idiopathic neutropenia is associated with decreased number of T-lymphocytes containing T-cell receptor excision circles. Eur J Haematol. 2012 Mar;88(3):210-23. Doi: 10.1111/j.1600-0609.2011.01722.x. Epub 2011 Nov 24.PMID:22092365.
4. Stavroulaki E, Kastrinaki MC, Pontikoglou C, Eliopoulos D, Damianaki A, Mavroudi I, Pyrovolaki K, Katonis P, Papadaki HA.Mesenchymal stem cells contribute to the abnormal bone marrow microenvironment in patients with chronic idiopathic neutropenia by overproduction of transforming growth factor-β1 . Stem Cells Dev. 2011 Aug;20(8):1309-18. Doi: 10.1089/scd.2010.0425. Epub 2010 Dec 27.PMID:21047210.
5. Antoniou KM, Papadaki HA, Soufla G, Kastrinaki MC, Damianaki A, Koutala H, Spandidos DA, Siafakas NM. Investigation of bone marrow mesenchymal stem cells (BM MSCs) involvement in Idiopathic Pulmonary Fibrosis (IPF). Respir Med. 2010 Oct;104(10):1535-42. Doi: 10.1016/j.rmed.2010.04.015. Epub 2010 May 18. PMID: 20483575.
6. Froudarakis ME, Papadaki HA, Klimathianaki M, Damianaki A, Pougounias M, Kotsianidis I, Astoul P.Thoracoscopic talc poudrage decreases T-lymphocytes in the peripheral blood. Respir Med. 2007 Jun;101(6):1212-7. Epub 2006 Dec 19. PMID: 17182238.
7. . Koumaki V, Damianaki A, Ximeri M, Pontikoglou C, Axioti F, Spanoudakis M, Eliopoulos GD, Papadaki HA. Pro-inflammatory bone marrow milieu in patients with chronic idiopathic neutropenia is associated with impaired local production of interleukin-10.Br J Haematol. 2006 Nov;135(4):570-3. Epub 2006 Oct 10. PMID: 17054669.
8. Psyllaki M, Damianaki A, Gemetzi C, Pyrovolaki K, Eliopoulos GD, Papadaki HA. Impaired megakaryopoiesis in patients with chronic idiopathic neutropenia is associated with increased transforming growth factor beta1 production in the bone marrow. Br J Haematol. 2006 Sep;134(6):624-31.PMID: 16938119.
9. Papadaki HA, Damianaki A, Pontikoglou C, Pyrovolaki K, Eliopoulos DG, Stavroulaki E, Eliopoulos GD.Increased levels of soluble flt-3 ligand in serum and long-term bone marrow culture supernatants in patients with chronic idiopathic neutropenia Br J Haematol. 2006 Mar;132(5):637-9. PMID: 16445839.
10. Papadaki HA, Tsagournisakis M, Mastorodemos V, Pontikoglou C, Damianaki A, Pyrovolaki K, Stamatopoulos K, Fassas A, Plaitakis A, Eliopoulos GD. Normal bone marrow hematopoietic stem cell reserves and normal stromal cell function support the use of autologous stem cell transplantation in patients with multiple sclerosis.Bone Marrow Transplant. 2005 Dec;36(12):1053-63. PMID: 16205726.
11. Papadaki HA, Stamatopoulos K, Damianaki A, Gemetzi C, Anagnostopoulos A, Papadaki T, Eliopoulos AG, Eliopoulos GD. Activated T-lymphocytes with myelosuppressive properties in patients with chronic idiopathic neutropenia. Br J Haematol. 2005 Mar;128(6):863-76. PMID: 15755293.
12. Papadaki HA, Kosteas T, Gemetzi C, Damianaki A, Anagnou NP, Eliopoulos GD. Acute myeloid/NK precursor cell leukemia with trisomy 4 and a novel point mutation in the extracellular domain of the G-CSF receptor in a patient with chronic idiopathic neutropenia. Ann Hematol. 2004 Jun;83(6):345-8. Epub 2004 Mar 11. PMID: 15014900.
13. Koumaki V, Papadaki HA, Stefanaki K, Damianaki A, Gemetzi C, Katonis P, Vrentzos G, Eliopoulos GD. Increased cell apoptosis in bone marrow trephine biopsies and immunomagnetically isolated myeloid progenitor cells in patients with chronic idiopathic neutropenia. Ann Hematol. 2003 Oct;82(10):641-5. Epub 2003 Aug 2. PMID: 12904900.
14. Papadaki HA, Eliopoulos AG, Kosteas T, Gemetzi C, Damianaki A, Koutala H, Bux J, Eliopoulos GD. Impaired granulocytopoiesis in patients with chronic idiopathic neutropenia is associated with increased apoptosis of bone marrow myeloid progenitor cells.    Blood. 2003 Apr 1;101(7):2591-600. Epub 2002 Nov 27. PMID: 12517813.
15.  Kampa M, Hatzoglou A, Notas G, Damianaki A, Bakogeorgou E, Gemetzi C, Kouroumalis E, Martin PM, Castanas E. Wine antioxidant polyphenols inhibit the proliferation of human prostate cancer cell lines. Nutr Cancer. 2000;37(2):223-33. PMID: 11142097.
16. Damianaki A, Bakogeorgou E, Kampa M, Notas G, Hatzoglou A, Panagiotou S, Gemetzi C, Kouroumalis E, Martin PM, Castanas E.Potent inhibitory action of red wine polyphenols on human breast cancer cells.   J Cell Biochem. 2000 Jun 6;78(3):429-41. PMID:   10861841.
17. Kampa M, Bakogeorgou E, Hatzoglou A, Damianaki A, Martin PM, Castanas E.Opioid alkaloids and casomorphin peptides decrease the proliferation of prostatic cancer cell lines (LNCaP, PC3 and DU145) through a partial interaction with opioid receptors.   Eur J Pharmacol. 1997 Sep 24;335(2-3):255-65. PMID: 9369381.